Targeting Immunometabolism in Autoimmune Diseases and Inflammation
Event Date: October 22, 2019
Deadline to Submit Abstracts: August 23, 2019
A large unmet medical need persists across the spectrum of autoimmune and inflammatory diseases. Emerging evidence suggests that immune cell fate is tightly regulated by changes in metabolic programming, including aerobic glycolysis (the Warburg effect), fatty acid synthesis and oxidation, and mitochondrial activity. Modulation of these pathways by cytokines, growth factors, and microbial products, as well as nutrient availability, controls the ability of lymphocytes to proliferate and produce specific immune effector molecules. Consequently, changes in immune cell metabolism can have a major impact on the progression and resolution of autoimmune and inflammatory diseases.
This symposium will explore the immunometabolic pathways that govern innate and adaptive immune cell activation, with a view to highlighting core pathways and specific enzymes that are likely therapeutic targets for autoimmune diseases and dysregulated inflammation.
To register for this event, please visit the main website at: www.nyas.org/IM2019